瘢痕子宫阴道分娩应用欣母沛预防产后出血

Scar uterus vaginal application of hemabate preventing postpartum hemorrhage

目的:探讨欣母沛用于瘢痕子宫阴道分娩预防产后出血的有效性、安全性。方法:选择瘢痕子宫阴道分娩的产妇90例,分为试验组(42例)与对照组(48例)。试验组在胎儿娩出后常规肌内注射缩宫素的基础上,同时应用欣母沛肌内注射;对照组则同时应用益母草针肌内注射。比较两组产后2 h及24 h出血量、产后出血发生率、药物不良反应发生率。结果:试验组与对照组的产后2 h出血量、24 h出血量、产后出血发生率比较,试验组均少于对照组,两组比较差异有统计学意义(P<0.05)。试验组与对照组的不良反应发生率比较,差异无统计学意义(P>0.05)。结论:欣母沛对于瘢痕子宫阴道分娩产妇发生产后出血的防治,较益母草针疗效明显,不良反应少。

Objective Observe the validity and security of Hemabate on the prevention of postpartum hemorrhage for secondary pregnancy of women with scarred uterus by vaginal delivery.Methods 90 cases of women with scarred uterus choose vaginal delivery on the secondary pregnancy were randomly divided into experimental group（42 cases） and control group（48 cases）.In the experimental group,on the basis of conventional intramuscular injection of oxytocin after the delivery of baby, women were given the intramuscular injection Hemabate simultaneously.While in the control group,women were given intramuscular injection Leonurus and oxytocin simultaneously.Compare the incidence of postpartum hemorrhage,the amount of postpartum bleeding in the first 2 and 24 hours and the adverse effects rate between the experimental group and the control group.Results Cmparing the experimental group with the control group in the incidence of postpartum hemorrhage and the amount of postparttma bleeding in the first 2 and 24 hours,the experimental group is less than the control group with statistical meanings（P 〈 0.05）.Comparing the adverse effects rate between the control group and the experimental group,there was no statistically significant difference（P 〉 0.05）.Conclusion Hemabate has a better clinical efficacy and less side effect than the Leonurus on the prevention and treatment of postpartum hemorrhage for the women with scarred uterus choose vaginal delivery.