EB病毒感染对住院新生儿血小板减少的影响

Epstein-Barr Virus Infection of Newborn Thrombocytopenic

目的探讨EB病毒感染对住院新生儿血小板减少的影响。方法分析2年来本院收治的96例新生儿血小板减少患儿,均检测EB病毒衣壳Ig M抗体、早期抗原IgG抗体及检测EBV DNA测定EB病毒;并对其母亲进行同期检测。结果 96例血小板减少患儿中检出EB病毒感染34例,其中30例(31.25%)检测出EBV DNA阳性,EBV-CAIgM阳性10例(10.42%),EBV-EA-D-IgG阳性19例(19.79%);患儿母亲确证感染23例,其中EBV DNA阳性20例,EBV-CA-IgM阳性7例,EBV-EA-D-IgG阳性10例。结论 EB病毒感染引起住院新生儿血小板减少症患者程度重,合并症多且恢复慢,如早诊断并及时治疗可取得较好疗效。

Objective Inquired into EB virus infection of newborn thrombocytopenic. Methods A analysed 96 cases of newborn thrombocytopenic in 2 years,determine the IgM antibodies of EB virus capsid and IgG antibodies,than diagnostic the EBV DNA of EB virus. Their mothers was simultaneously tested as well. Results 96 cases of newborn with thrombocytopenia in 34 cases with EB virus infection. Among them,30 cases（ 31. 25%） were detected EBV DNA positive; 10 cases（ 10. 42%） were EBV-CA-IgM positive; 19cases（ 19. 79%） of EBV-EA-D-IgG positive; mothers were confirmed to be infected in 23 cases,20 of them were EBV DNA positive and seven of them were EBV-CA-IgM positive,ten cases were EBV-EA-D-IgG positive. Conclusion EB virus infection of newborn thrombocytopenic show the symptoms such as critical condition,various of complications and slow recovery. Better curative effect can be accomplished if it gets the diagnosis and treatment on time.