评估肥胖型和非肥胖型多囊卵巢综合征临床指标的差异

Assess fueling and fueling clinical index difference of polycystic ovary syndrome

目的评估肥胖型和非肥胖型的多囊卵巢综合征患者(PCOS)临床相关指标的差异。方法选取PCOS的患者,按照体重指数将其分选为肥胖组和非肥胖组,符合筛选条件的各31例。检测性激素水平、血糖水平(FBG)和胰岛素(FINS)的水平,并计算出相应的胰岛素抵抗指数(IRI),采用超声检测腹部脂肪的厚度以及内脏脂肪厚度,比较两组的差异。结果 FSH值、LH值、LH/FSH的比值比较,两组比较差异有统计学意义(P<0.05);FBG值、FINS值以及IRI值,肝前脂肪的厚度,肝前皮下的脂肪厚度,内脏脂肪的厚度以及腹部皮下的脂肪厚度比较,肥胖组高于非肥胖组(P<0.5)。结论肥胖型患者其高雄激素、高胰岛素和胰岛素抵抗更为严重,另外患者内脏脂肪堆积更为明显,临床治疗应该区别对待。

Objective To assess obese and non-obese patients with polycystic ovary syndrome（PCOS）the differences of clinically relevant indicators.Methods Patients with PCOS were separated obese and non-obese group by BMI, and each group has 31 cases. Detect sex hormone levels and blood glucose （FBG）level and insulin（FINS）, and calculate the corresponding insulin resistance index（IRI）, measure the thickness of abdominal fat and visceral fat, comparing the difference between the two groups. Results Compare the value of FSH, LH, LH/FSH ratio, two groups have statistical difference（P〈0. 05）;FBG value, FINS and IRI value, the fat thickness, obesity group was higher than non-obese group（P 〈0. 05）. Conclusion Obesity patients show more serious high androgen and insulin and insulin resistance, and visceral fat accumulation is more obvious, clinical treatment should be treated differently.