腹腔镜与开腹手术在结直肠癌治疗中的应用对比分析

Laparoscopic versus open surgery in the treatment of colorectal cancer: a comparative study

目的比较腹腔镜与开腹结直肠癌切除术临床疗效,探讨腹腔镜结直肠癌切除术的临床价值。方法选择2009年6月至2012年1月中山大学孙逸仙纪念医院胃肠外科收治的结直肠癌患者98例作为研究对象,其中52例接受腹腔镜手术,46例接受开腹手术,比较两组结直肠癌患者的手术时间、术中出血量、淋巴结清扫范围、术后腹腔(或盆腔)引流量、术中术后并发症、肛门恢复排气排便时间、术后住院时间等指标。结果腹腔镜组与开腹组清扫淋巴结数目、术中出血量、术中术后并发症发生率差异均无统计学意义;手术时间、术后腹腔(或盆腔)引流量、术后肛门恢复排气排便时间、术后住院时间等方面差异有统计学意义(P<0.05)。结论腹腔镜结直肠癌切除术是可行和安全有效的,与开腹手术对比有较多优点,适合在临床进一步推广应用。

Objective To compare the effect of laparoscopic surgery and open operation in the treatment of colorectal cancer, Methods From June 2009 to January 2012, ninety-eight cases of eoloreetal cancer were treated, fifty-two of whom underwent laparoscopic surgery and forty-slx underwent open surgery. Operation time, volume of blood loss, the total number of lymph nodes, postoperative abdominal or pelvic drainage, intraoperative or postoperative complications, the first exhaust time, and postoperative hospitalization stay were compared. Results There were no significant differences between laparoscopic group and open surgery group in the total number of lymph nodes, blood loss, intraoperative or postoperative complication rate. In the aspects of operative time, postoperative abdominal or pelvic drainage, the first exhaust time, postoperative hospitalization stay, the difference was statistically significant （P 〈 0.05）. Conclusions Laparoscopic colorectal resection is feasible, safe and effective, and has a number of advantages compared with open operation. It is suitable for further clinical application.