负压创面治疗技术的研究应用进展

Research progress on application of negative pressure wound therapy

负压创面治疗技术(NPWT)是最近十几年来创立并开展的创面治疗新方法,近年已被广泛用于各种急慢性创面的治疗而且取得了确切的疗效。本文概括比较了负压创面治疗技术的两个关键技术:封闭负压引流技术和封闭负压辅助闭合技术,阐明了二者是原理相同,但选材、方法和适应证不同的两种技术。另外,本文也归纳了负压创面治疗技术促进伤口愈合的作用机制,主要是通过促进创面血液循环、减轻水肿、抑制细菌繁殖、机械应力促使肉芽组织生长、抑制细胞凋亡从而促进创面愈合。同时,本文还总结了近年来临床上将NPWT技术运用于各种急慢性创面治疗的进展。最后,作者也对负压治疗技术的发展前景提出了自己的看法与见解。

The technique of negative pressure wound therapy（NPWT）,initially used for better wound healing,has been widely applied to all kinds of refactory wound. This article reviewed the two important techniques including VSD and VAC of NPWT and indicated that the two are different techniques sharing the same principle,but with different materials,methods and indications. Furthermore,this review updated and made a induction of the enhancing mechanism that NPWT can promote wound blood circulation,reduce swelling,inhibit bacterial growth,stimulate growth of granulation tissue to mechanical stress,inhibit cell apoptosis thereby helping wound healing. Meanwhile,the author also summarized recent progress in clinical applications of NPWT used in a variety of acute and chronic wound treatment. In the end,the author provided a prospect for the further development of NPWT in this review.