樟树叶化学成分的研究

A Study on the Chemical Constituents in the Leaves of Cinnamomum camphora

本文研究了樟树叶的化学成分。主要采用硅胶、Sephadex LH-20凝胶和聚酰胺等柱层析方法对樟树叶的化学成分进行分离纯化,并根据理化性质、波谱数据(1H NMR,13C NMR)鉴定化合物的结构。从樟树叶的甲醇提取物中分离鉴定出9个化合物,分别为山柰酚-3-O-β-D-葡萄糖苷(1)、槲皮素-3-O-β-D-鼠李糖苷(2)、槲皮素-3-O-β-D-葡萄糖苷(3)、异鼠李素-3-O-β-D-葡萄糖苷(4)、黑色五味子单体苷(5)、山奈酚-3-O-β-D-芸香糖苷(6)、异鼠李素-3-O-β-D-芸香糖苷(7)、新芝麻脂素(8)和maculatin(9)。化合物1为首次从樟属中分离得到,化合物4、5、8为首次从樟科植物中分离得到。

To investigate the chemical constituents of the leaves of Cinnamomum camphora. Silica gel, Sephadex LH-20 and Polyamide column chromatography were applied for isolation of the constituents. Nine compounds （1-9） were isola- ted and their structures were identified by spectroscopic analysis as foUowing：kaempferol-3-O-β-D-glucopyranoside （1）, quercetin-3-O-β-D-rhamnopyranoside （ 2 ）, quercetin-3-O-β-D-glucopymnoside （ 3 ）, isorhamnetin-3-O-β-D-glucopyrano- side （4）, schizandriside （ 5 ）, kaempferol-3-O-β-D-rutinoside （ 6 ）, isorhanmetin-3-O-β-D-rutinoside （ 7 ）, neo-sesamin （8） and maculatin （9）. Compound I was isolated from Cinnamomum spp. for the first time. Compounds 4,5 and 8 were isolated from Lauraceae for the first time.