樟树木化学成分研究

Studies on the Chemical Constituents of the Stem of Cinamomum Camphora

采用硅胶、聚酰胺柱层析及重结晶方法对樟树木化学成分进行分离纯化,并根据理化性质和光谱数据分析鉴定得到10个化合物,分别是:β-谷甾醇(β-sitosterol,1)、槲皮素(quercetin,2)、山奈酚(kaempferol,3)、(8R,8'R)-3,3',4,4'-四甲氧基-9-氧代-8-8',9-O-9'木脂素((8R,8'R)-3,3',4,4'-tetramethoxy-9-oxo-8-8',9-O-9'lignans,4)、胡萝卜甙(daucosterol,5)、槲素-7-O-β-D-葡萄糖苷(Quercetin-3-O-β-D-glucoside,6)、槲皮素-3-O-α-L-鼠李糖苷(Quercetin-3-O-α-L-rhamnoside,7)、槲皮素-3-O-β-D-葡萄糖苷(Quercetin-3-O-β-D-glucoside,8)、芦丁(rutin,9)、齐墩果酸(oleanolic acid,10)。化合物1、2、3、5、6、10均为首次从樟树中分离得到。

The constituents of the stem of Cinamonum Camphora were isolated by column chromatography on silicagel, polyamide and recrystallization. Their structures were elucidated by physieochemieal properties and spectral analysis. Ten compounds were isolated and identified as/3-sitosterol （ 1 ）, queroetin （ 2 ）, kaempferol （ 3 ）, （ 8R, 8＇ R ） -3,3＇, 4,4＇-tetra- methoxy-9-oxo-8-8＇ ,9-O-9＇lignans （ 4 ）, daucosterol （ 5 ）, Quercetin-3 -O-β-D-glucoside （ 6 ）, Quereetin-3-O-α-L-rhaInno- side （7）, Quercetin-3 -O-β-D-glucoside （8）, rutin （ 9）, oleanolic acid （ 10 ）. Compound 1,2,3,5,6,10 were obatained from Cinamonum Camphora for the first time.