2000-2009年浙江省肿瘤登记地区甲状腺癌发病和死亡情况分析

Incidence and mortality of thyroid cancer in six cancer registries of Zhejiang province, 2000-2009

目的 研究浙江省肿瘤登记地区2000 2009年甲状腺癌发病与死亡的状况.方法 2000-2009年甲状腺癌发病与死亡数据来源于浙江省6个肿瘤登记地区,并经浙江省肿瘤防治办公室审核、整理和统计分析,计算甲状腺癌发病和死亡的粗率、标化率及变化趋势.结果 2000 2009年浙江省肿瘤登记地区甲状腺癌合计发病率为6.93/10万,男性发病远低于女性,男性与女性发病比值为1：3.43.发病率从2000年的3.62/10万,上升到2009年的11.42/10万,年度变化百分比（annual percent change,APC）为16.32％（95％可信区间为12.90％ ～ 19.85％）.2000 2009年浙江省肿瘤登记地区甲状腺癌合计死亡率为0.27/10万,男性与女性死亡比值为1：1.12.20002009年甲状腺癌死亡率无显著变化,年度变化百分比（APC）为2.14％（95％可信区间为-7.10％ ～12.30％）.发病率从15岁开始上升明显,在55岁～组达到高峰.死亡率在O～54岁处于较低水平,从55岁开始死亡率明显上升,在85岁～组达到高峰.结论 应重视青少年、中青年人群的甲状腺癌危险因素防控工作.

Objective To investigate the incidence and mortality rates of thyroid cancer in Zhejiang province during 2000 to 2009.Methods The data of thyroid cancer were collected from six cancer registries in Zhejiang province and the incidence and mortality rates of thyroid cancer were analysed.Results The mean annual incidence rate of thyroid cancer in Zhejiang cancer registration areas was 6.93/100 000 during 2000 to 2009,and male/female ratio was 1： 3.43.The incidence rate was 3.62/100 000 in 2000 and it increased to 11.42/100 000 in 2009,with the annual percent change （APC） of 16.32％ （95％ confidence interval：12.90％-19.85％）.The mean annual mortality rate of thyroid cancer was 0.27/100 000 during 2000 to 2009,and male/female ratio was 1： 1.12.The mortality showed a rising trend without a distinct fluctuation from 2000 to 2009,the APC was 2.14％ （95％ confidence interval：from-7.10％ to 12.30％）.The incidence showed a rising trend with the increase of ages after 15 years old,and peaked at 55-60 years old.The mortality was low before 54 years old,but showed a rising trend with a distinct fluctuation after 55 years old,and peaked at 85-90 years old.Conclusion The prevention and control of risk factors for thyroid cancer in young and middle-aged people is key to decrease the incidence and mortality of thyroid cancer.