从微剂量学到纳米剂量学——连接放射生物和辐射物理的桥梁

From Microdosimetry to Nanodosimetry——the Link between Radiobiology and Radiation Physics

本文描述了辐射与生物体相互作用的宏观量和微观量之间的联系,介绍了从微剂量学到纳米剂量学的发展趋势和最新成果,以及测量、计算其中的微观物理量的方法;探讨了微剂量学和纳米剂量学与辐射生物学之间的关系,以及它们在辐射防护和放射治疗等应用中存在的问题和未来进一步发展的方向。

The link between micro- and macro-parameters for radiation interactions that take place in living biological systems is described in this paper. Meanwhile recent progress and development in microdosimetry and nanodosimetry are introduced, including the methods to measure and calculate these micro- or nano-parameters. The relationship be- tween radiobiology and physical quantities in microdosimetry and nanodosimetry was presented. Both the current problems on their applications in radiation protection and radiotherapy and the future development direction are pro- posed.