小剂量低压力灌洗在急性中毒并发消化道出血患者中的临床应用

The Clinical Usage of Small Dose and Low Pressure Lavage in Gastrointestinal Hemorrhage Induced by Acute Poisoning

目的探讨小剂量低压力灌洗在急性中毒所致消化道出血患者中的应用效果。方法收集2011年1月-2012年12月收治的急性中毒致消化道出血患者的临床资料。根据其是否接受洗胃治疗,将患者分为单纯接受传统治疗措施的对照组和接受小剂量低压力灌洗治疗的观察组。观察组和对照组患者的年龄、性别和服毒量等指标之间的差异无统计学意义。记录患者的年龄、中毒后至救治的时间、服毒量以及休克情况(血压、脉搏)和并发症等情况。根据患者的年龄、休克情况以及并发症情况,进行ROCKALL评分,以评估两组患者经治疗后的死亡危险程度之间的差异。结果观察组高、中死亡危险患者的构成比低于对照组,差异有统计学意义(P<0.05)。结论小剂量低压力灌洗能一定程度上改善急性中毒所致消化道出血患者的预后。

Objective To explore the effects of small dose and low pressure lavage on gastrointestinal hemorrhage induced by acute poisoning. Methods We collected the clinical data of all the patients diagnosed as gastrointestinal hemorrhage induced by acute poisoning treated between January 2011 and December 2012. The patients were divided into two groups： control group and treatment group, according to the different treatments they underwent. The control group received traditional treatment only, while the treatment group received small dose and low pressure lavage as well as the traditional treatment. After recording the ages, poisoning dose, pretreatment time, shock and complications, we evaluated the risk of death by calculating ROCKALL scores. Results The differences of ages, sexes, and poisoning dose between these two groups were not significant. However, the death rate in high and middle risk patients of the treatment group was significantly lower than that of the control group （P 〈 0.05）. Conclusion The small dose and low pressure lavage can improve the prognosis of the gastrointestinal hemorrhage induced by acute intoxication.