复方莪术散在子宫内膜异位症术后的应用

Clinical Application of Compound Rhizoma Curcumae Powder for Post-operative Treatment in Patients with Endometriosis

目的：探讨复方莪术散在子宫内膜异位症腹腔镜术后的价值。方法：将Ⅱ~Ⅲ期子宫内膜异位症腹腔镜术后肾虚血瘀证患者120例回顾性随机分为3组，复方莪术散组（n=40）于术后7 d开始服用复方莪术散；曲普瑞林组（n=44）术后7 d开始肌肉注射曲普瑞林,每4周1次；联合组（n=36）给药方式同复方莪术散组及曲普瑞林组。结果：在临床疗效方面复方莪术散组、曲普瑞林组及联合组比较，受孕率、症状改善率均提高，复发率下降,3组临床疗效比较差异无统计学意义（P＞0.05）,莪术散组不良反应发生率（20%）较曲普瑞林组（79%）和联合组（89%）明显降低（P＜0.01）。结论：腹腔镜术后辅助复方莪术散，对提高子宫内膜异位症患者受孕率、降低复发率、改善疼痛有重要作用,且副作用少、费用低。

Objective To explore the Compound Rhizoma Curcumae Powder in endometriosis following val-ue of laparoscopic surgery. Methods A total of 120 patients with stage Ⅱ~Ⅲ endometriosis foiiowing laparo-scopic surgery complicated with kidney deficiency blood stasis syndrome were randomly divided into three groups. Curcumae Powder group（n=40） received the treatment of Compound Rhizoma Curcumae Powder since 1week after surgery; Triptorelin group（n=44） was given by intramuscular infection of Triptorelin 3.75 mg since 7 days after surgery and Joint group（n=36）was given both drugs. Results In the aspect of clinical efficacy, in all the three groups, the conception rate and symptoms improving period increased, the recurrence rate dropped significantly with no statistically significant difference （P〉0.05） at total effective rate and recurrence. The inci-dence of adverse reactions in Curcumae Powder group（20%） significantly decreased （P〈0.01）much less than Triptorelin group （79%） and the joint group （89%）. Conclusion Laparoscopic surgery assisted compound zedo-ary turmeric powder, to improve the endometriosis patients＇ conception rate, reduce the recurrence rate with less pain and less side effect and low cost.