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过氧化物酶体增殖物激活受体γ在免疫介导的再生障碍性贫血模型小鼠骨髓细胞中的表达 被引量:2

Expression of PPARγ in bone marrow of model mice of immune-mediated aplastic anemia mice model
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摘要 过氧化物酶体增殖物激活受体γ(PPARγ)是核激素受体超家族成员之一,为一种配体依赖性的转录因子[1],是脂肪形成所必需的因子[2].再生障碍性贫血(简称再障)的病理特征为脂肪细胞取代造血活跃的骨髓占据骨髓腔.有研究报道,再障患者增多的骨髓脂肪组织分泌多种因子,包括瘦素、TNF-α、胰抵抗素和脂联素等,统称为脂肪细胞因子.
出处 《中华血液学杂志》 CAS CSCD 北大核心 2014年第6期553-555,共3页 Chinese Journal of Hematology
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