2-DM大血管病变患者血清C-反应蛋白检测临床意义分析

Clinical Significance Analysis of Detection Serum C-reactive Protein in 2-DM Patients with Macrovascular Lesions

目的:探讨2-DM大血管病变患者血清C-反应蛋白检测的临床意义。方法:选择120例2-DM患者(合并大血管病变70例)研究对象,随机选择80例同期体检者作为对照人群,进行C-反应蛋白,血脂,空腹血糖测定。结果:2-DM患者C-反应蛋白水平均(3.76±1.02)mg/L高于体检(1.11±0.56)mg/L;70例合并大血管病变组患者C-反应蛋白(4.33±1.09)mg/L、体重指数(24.99±1.23)Kg/m2、胆固醇(2.87±0.56)mmol/L高于50例单纯2-DM组的(3.08±0.88)mg/L、(23.16±1.19)Kg/m2、(1.68±0.47)mmol/L,两组甘油三脂、空腹血糖比较无显著性差异。结论:C-反应蛋白与2-DM大血管病变的发生、发展、预后密切相关,对于2-DM患者进行C反应蛋白水平监测具有重要的临床意义,可作为2-DM常规检测项目之一。

Objective：To investigate the clinical significance of detection serum C-reactive protein in 2-DM macrovascular lesions patients.Methods：Select 120 2-DM patients （70 cases with macrovascular lesions） as research object, randomly selected 80 cases of physical examination as control group, determination C-reactive protein,lipid,fasting blood glucose.Results：C-reactive protein levels in C-2-DM patients were （3.76±1.02） mg/L was higher than examination（1.11±0.56） mg/L;70 cases with macrovascular lesions C-reactive protein（4.33±1.09） mg/L,body mass index（24.99±1.23）Kg/m2,cholesterol（2.87±0.56）mmol/L is higher than that of group 2-DM simple 50 cases（3.08±0.88） mg/L,（23.16±1.19）Kg/m2,（1.68±0.47） mmol/L,there was no significant difference between triglyceride,fasting blood glucose.Conclusion：Closely related to the occurrence,development,prognosis of C-reactive protein and 2-DM macroangiopathy,has important clinical significance for patients with 2-DM to monitor protein levels of C-reaction, can be used as one of the conventional 2-DM detection project.