甲状腺功能亢进危象49例分析

Analysis of 49 Cases of Thyroid Crisis

目的提高临床医师对甲状腺功能亢进危象的认识。方法在中国期刊网全文数据库中检索,对符合诊断标准的40篇病例报告文献,进行分析。结果共49例患者,其中死亡11例,存活38例。发病诱因手术18例,感染15例,占总患者65.31%(33/49)。死亡组及时就诊率低于存活组,死亡组中体温不升发生率及基础病合并率高于存活组。11例死亡者中9例死于心衰。结论感染和手术是甲亢危象发生的主要诱因,合并基础病和未能及时诊治的患者,病死率相对较高。病程中出现体温不升者预后不佳。心衰是患者的主要死亡原因。

Objective To improve knowledge on thyroid crisis. Methods A retrospective analysis of 49 cases with thy- roid crisis was performed. All cases were related from Chinese Journal Full - text Database from 2000 to 2011. Results In 49 cases,death group were 11. Survival group were 38. Predisposing factors of all case： surgical operations 18 ,in- fection 15. The rates of seeking medical advice in time were higher in the survival group than in the death group. Inci- dence of hypothermia and complicated ratio of primary disease were higher in death group than in the survival group. 9 of 11 death patients died from heart failure. Conclusions The main inducement factors of thyroid crisis are surgical operations and infection. Combined with primary disease and seeking medical advice out of time have high mortality. Hypothermia has bad prognosis during the course of disease. Heart failure is the main death cause.