摘要
目的:获得连续提取野葛葛粉和总黄酮的生产工艺。方法:测定野葛提取葛粉前后总黄酮含量变化,为获得提取葛粉后残渣再提取总黄酮的理论依据;采用正交试验优化总黄酮的提取工艺,最后确定整个连续提取工艺并进行中试生产验证。结果:野葛提取葛粉后残渣中总黄酮残留量近半,值得进一步提取总黄酮。总黄酮的提取工艺条件经优化后确定为8倍量的80%乙醇为溶剂,回流提取1.5 h,连续提取3次。结论:工艺经中试生产验证,稳定可行,但需进一步优化。
Objective： To obtain a continuous extraction technology of starch and total flavonoids. Methods： First,detecting the total flavonoids content changes before and after starch extracted from P. lobata. To obtain theoretical basis for re-extract residue after extraction starch. Then,use orthogonal test to optimize the extraction process of total flavonoids. Finally,determine the entire extraction process and conduct continuous pilot production authentication. Results： The total flavonoids content nearly 50% in residue,it is worth to further extract. Optimized extraction conditions of total flavonoids is 8 times solvent of 80% alcohol,reflux extraction 1. 5 hours,repeated 2 times. Conclusion： The production process was enlarged validated,stability feasible,but need further optimization.
出处
《中国现代中药》
CAS
2014年第6期475-477,509,共4页
Modern Chinese Medicine
基金
重庆市教委科学技术研究项目(KJ111803)
关键词
野葛
葛粉
总黄酮
正交设计
连续提取工艺
Pueraria lobata（Willd.） Ohwi
Starch
Total Flavonoids
Orthogonal test
Continuous extraction technology
