多囊卵巢综合征患者IL-18的表达水平及其相关性研究被引量：2

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摘要目的:检测白细胞介素18(IL-18)在多囊卵巢综合征(PCOS)患者表达水平,探讨其与胰岛素(Insulin)和胰岛素抵抗指数(HOMA-IR)的关系。方法:检测实验组与对照组患者的体重指数(BMI)、IL-18、胰岛素(Insulin)、空腹血糖(FBG)水平,并计算HOMA-IR。研究IL-18水平与BMI、Insulin、FBG及HOMA-IR的相关性。结果:实验组患者的BMI、血清IL-18、Insulin及HOMA-IR明显高于对照组(P<0.05);实验组患者血清IL-18水平与Insulin、HOMA-IR呈正相关(P<0.05)。结论:IL-18在PCOS患者中的水平明显升高,且与患者的Insulin水平、HOMA-IR呈正相关,IL-18在PCOS的发病过程中起到重要作用。

作者刘俐伶庞丽红邓丽殷艳

机构地区广西医科大学第一附属医院妇产科

出处《广西医科大学学报》 CAS 2014年第3期443-444,共2页 Journal of Guangxi Medical University

关键词多囊卵巢综合征 IL-18 INSULIN HOMA-IR

分类号 R711 [医药卫生—妇产科学]

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参考文献1

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