反相高效液相色谱法测定二硝酰胺铵的纯度

Determination of the Purity of Ammonium Dinitramide by RP-HPLC

采用Agilcent C18反相色谱柱（150mm×4．6mm，5μm），选用二元流动相乙腈（pH值为3．0的磷酸水溶液），在体积比为10：90、流速为1mL／min、柱温为30℃、检测波长为210nm的条件下，采用面积校正归一化法计算了二硝酰胺铵（ADN）的纯度。结果表明，当ADN的质量浓度为0．0001～0．001g／mL时，色谱峰面积与ADN标准样品质量浓度呈良好的线性关系A=51．73C＋5．442，相关系数为0．9980，平均回收率为98．33％～99．67％，相对标准偏差为0．49％。该方法结果准确可靠，操作简单实用，可用于ADN产品纯度分析。

The purity of ammonium dinitramide（ADN） was determined by area correction normalization method un- der such conditions as： Agilcent C18 column （ 150 mm × 4.6 mm, 5μm） at temperature 30℃, acetonitrile-phosphoric acid as binary mobile phase with pH value of 3.0 （volume ratio 10 ： 90） at flow rate of 1.0mL/min,UV detection wavelength 210nm. Results show that when mass concentration of ADN is in the range of 0. 000 1-0. 001 g/mL, there is a good linear relationship between the peak area of ehromatogram and ADN mass concentration：A= 51.73C ＋5. 442. The linear correlation coefficient is 0. 998 0, average recoveries is 98.33 %- 99.67 %, relative standard deviation is 0.49 %. This method is reliable and can be used to analyze the purity of ADN in practice.