尿毒营养膏对尿毒症维持性血透(MHD)患者的微炎症状态的影响

Influence of Niaodu cream on micro inflammation in MHD patients

目的:研究尿毒营养膏对维持性血液透析患者微炎症状态的影响。方法:将60例尿毒症维持性血液透析患者随机分为治疗组、对照组各30例。两组均给予常规治疗,治疗组在常规治疗基础上加服尿毒营养膏,疗程12周。观察两组在治疗前后基础营养指标、血红蛋白(HGB)、血清白蛋白(ALB)、C-反应蛋白(hs-CRP)、白细胞介素-6(IL-6)、β2-微球蛋白的水平。结果:两组患者治疗前后营养状况的比较有显著差异(P<0.05),治疗组HGB水平较治疗前上升,较对照组有统计学差异(P<0.05),治疗组ALB水平上升但无统计学意义(P>0.05),治疗组hs-CRP、IL-6水平较治疗前下降且低于对照组(P<0.05),治疗组β2-微球蛋白水平有下降趋势,但无统计学意义。结论:尿毒营养膏可以改善维持性血液透析患者的营养状况,降低维持性血液透析患者的CRP、IL-6水平,能提升HGB水平,改善其贫血状态。

Objective： To observe clinical influence of Niaodu cream on micro inflammation in MHD patients. Methods： 60 patients were randomly divided into two groups, 30 cases for each. All groups were given routine medicine, the treatment was given Niaodu cream more, basic nutrition indicators, HGB, ALB, hs-CRP, IL-6,β2-microglobulin levels were compared before and after treatment. Results： The difference of nutritional status between two groups was obvious （P〈0.05）, HGB levels in the treatment was higher with a statistical differencethan that before treatment （P〈0.05）, while ALB levels in the treatment was higher with no statistical difference （P〉0.05）, hs-CRP, IL-6 levels in the treatment was reduced and lower than that in the control （P〈0.05）,β2-microglobulin levels in the treatment tend to be reduced with no statistical significance. Conclusion： Niaodu cream can improve nutritional status and reduce CRP, IL-6 levels in MHD patients, improve anemia status through adjustment of HGB levels.