摘要
环肽astins是紫菀比较有特色的一类化学成分,至今此类型环肽只在该种中发现。其结构新颖,是紫菀抗肿瘤活性的主要成分。在植物分类学及抗肿瘤新药开发上都具有较高的研究开发价值。本文以紫菀astins为主要对象,对其化学结构、生物活性、构效关系方面的研究进行了综述。
Cyclic peptide astins are distinctive chemical constituents from Aster tataricus L. and only dis- covered in this plant. Besides their interesting structures, these cyclopeptides also show potential biologi- cal activities. They are valuable for plant taxonomy and anti-tumor drug development. This paper focused on the research advances of their chemical structures, biological activities and structure-activity relation- ship.
出处
《中国野生植物资源》
2014年第3期32-35,43,共5页
Chinese Wild Plant Resources
基金
国家自然科学基金项目(30772702)
关键词
紫菀
环肽
构效关系
Aster tataricus
cyclopeptides
structure-activity relationship
