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血糖指标水平与阿尔茨海默病的相关性分析 被引量:4

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摘要 目的探讨血糖指标水平与阿尔茨海默病(AD)之间的相关性,为糖尿病与AD关系的研究提供科学依据。方法选取2012年6月-2013年9月于该院就诊经简明精神状态量表(MMSE)诊断为AD的患者68例为研究组,另选取健康同龄人36例为对照组,测量2组患者的身高、体质量、体质量指数(BMI)、空腹胰岛素(FINS)、空腹血糖(FPG)、胰岛素抵抗指数(HOMA-IR)、胰岛素降解酶(IDE)等指标。结果 2组FINS、HOMA-IR和FPG差异无统计学意义(P>0.05)。研究组血清IDE水平明显低于对照组,差异有统计学意义(P<0.05)。结论 FINS、FPG及HOMA-IR与AD患病无显著相关性,而血清IDE水平与AD呈显著相关性,由此对血清IDE水平检测可作为糖尿病并发AD的评定及预防。
出处 《临床合理用药杂志》 2014年第19期129-130,共2页 Chinese Journal of Clinical Rational Drug Use
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