布鲁氏菌病防治基础研究现状与展望

Status and Perspective of Basic Research of Prevention and Control of Brucellosis

布鲁氏菌病(简称布病)是由布鲁氏菌属细菌侵入机体引起的人畜共患传染病.近年来,布病疫情在世界范围内呈反弹趋势,我国尤甚.进入2000年以后,人间布病在我国成为报告发病数上升速度最快的传染病之一,令我国布病防治形势严峻.为了明确我国布病防治工作的现状和需求、最新研究现状和研究动态以及面临的挑战和机遇,深入研讨分析我国布病防治研究中的重大科学和关键技术问题,凝练和提出今后我国布病防治研究发展中亟需关注、解决的重要基础科学问题,在国家自然科学基金委员会资助下,由中国疾病预防控制中心地方病控制中心主办,哈尔滨医科大学、中国疾病预防控制中心传染病预防控制所和内蒙古地方病防治研究中心共同协办,于2013年6月21日召开了由来自全国布病防治与基础研究领域专家共同参加的"布鲁氏菌病防治基础研究发展战略研讨会".会议在我国布病疫情最重的省份内蒙古自治区呼和浩特市召开,中国疾病预防控制中心传染病预防控制所、军事医学科学院疾病预防控制所、石河子大学、中国兽医药品监察所等19家从事布病防治与基础研究的科研院所、高等院校、疾病防治机构的40余位专家参加了此次会议.现结合文献资料以及本次会议的内容,对国内外布病流行现状、研究进展,以及影响我国布病防治的亟需解决的科学问题和建议作一综述.

Brucellosis is a kind of zoonotic infection caused by bacteria of Brucella. Epidemic of brucellosis rebounded worldwide especially in China in recent years. Since the beginning of the 21st century, human brucellosis has become one of the infectious diseases with the largest number of reported new cases, which puts great stress on the prevention and control of brucellosis in China. To make clear the status quo and requirement, the latest research development, and the potential challenges and opportunities of the prevention and control of brucellosis in China, the seminar about the development strategies of the basic research related to the prevention and control of brucellosis was held to thoroughly discuss the major scientific and critical technical issues, and to put forward the basic scientific issues that need urgent attention in the following practice of the prevention and control of brucellosis in China. This seminar was sponsored by National Natural Science Foundation of China, organized by Center for Endemic Disease Control, China CDC, and co-organized by Harbin Medical University, Institute for Communicable Disease Control and Prevention, China CDC, and Center for Endemic Disease Control and Prevention of Inner Mongolia. This seminar was held in Hohhot, Inner Mongolia Autonomous Region, the most affected province of brucellosis in China, on June 21st, 2013. More than 40 experts in the field of brucellosis basic research, prevention and control participated in the seminar, who were from 19 institutes of scientific research, colleges and universities, such as Institute for Communicable Disease Control and Prevention of China CDC, Institute of Disease Control and Prevention of Academy of Military Medical Sciences, Shihezi University, and China Institute of Veterinary Drug Control. On the basis of the literature and the contents of this seminar, this review summarizes the epidemic status and research development of brucellosis, and puts forward the issues and advices that need to be resolved urgently in the prevention and control of brucellosis.