摘要
We have read with great interest the recent article “Cellular mechanism of cardiac alternans: an unresolved chicken or egg problem” by Zang and Xia (2014), published in Journal of Zhejiang University- SCIENCE B (Biomedicine & Biotechnology). The authors proposed that both calcium handling and electrical components of cardiac cells could be the cellular mechanism of cardiac alternans, and identifying the main mechanism of cardiac alternans could help to cure targeted patients with heart failure. Here,
由于钙离子在心肌细胞兴奋-收缩偶联中发挥着核心作用,低钙血症可诱发心肌病。临床上,由于低钙血症导致的T波电交替和急性心衰罕见,极易被忽视或误诊。研究显示,低钙血症引起的T波电交替和急性心衰往往是可逆的,因而及时纠正严重低钙血症十分重要。本文报告一例慢性甲状旁腺功能减退症患者,由于严重的低钙血症引起T波电交替和急性心衰发作,在迅速纠正低钙血症后,患者病情得以缓解,T波电交替完全消失,心功能部分恢复。通过复习该病例,有助于临床医生重视可引起T波电交替和心衰的可逆性因素—低钙血症。