腹腔镜在直肠癌合并T2DM患者中的疗效和安全性研究

A study on efficacy and safety of laparoscopy in patients with rectal cancer and T2DM

目的探讨腹腔镜切除对直肠癌合并T2DM患者的疗效。方法回顾性分析2010年7月-2012年7月我院收治的直肠癌合并T2Dbl的88例患者，分为观察组和对照组，其中观察组39例患者进行腹腔镜手术，对照组49例患者进行传统开腹手术。对两组的疗效及安全性进行比较。结果两组相比，观察组在术中的切口长度、失血量、开始进流食时间、排气时间以及住院天数等方面均优于对照组，且观察组患者并发症的发生率（5．13％）显著低于对照组（14．29％），其差异在统计学上有意义（P〈0．05）。两组在淋巴结清扫数、手术时间等方面的差异不显著，且观察组患者术后术后镇痛泵使用率（71．79％）和对照组（75．51％）无显著差异，其无统计学意义（P〉0．05）。结论腹腔镜手术对直肠癌合并T2DM患者，能减少并发症的发生，并且疗效优于传统疗法，值得推广应用。

Objective To explore and observe the curative effect of laparoscopic resection in patients with rectal cancer and T2DM. Methods A retrospective analysis of 88 cases patients with rectal cancer and T2DM in our hospital from July 2010 to July 2012 was conducted.The patients were divided into the observation group and the control group;while the 39 patients of the observation group underwent laparoscopic operation,the 49 cases in the control group underwent conventional open operation.The efficacy and safety of the two groups were compared. Results Under comparison,the length of incision,blood loss,starting time of flowing food,exhaust time and hospital stay in operation of the observation group were better than those of the control group,and the incidence of complications in patients with the observation group （5.13%） was significantly lower than that of the control group （14.29%）,the difference was statistically significant（P 〈 0.05）.Differences in lymph node yield,operation time and other aspects of the two groups were not signlficant,and the postoperative analgesia pump rate（71.79%） of the observation group and the control group（75.51%） showed no significant difference, which was not statistically significant（P ~ 0.05）. Conclusion Laparoscopic operation in the treatment of rectal cancer complicated with T2DM can reduce the incidence of complications,and its curative effect is better than the traditional therapy, therefore worthy of popularization and application.