主动脉瓣钙化与冠心病的关系研究

Study of association between the aortic valve calcification and coronary artery disease

目的探讨主动脉瓣钙化与冠心病发病之间的关系。方法回顾性研究同期行冠状动脉造影检查和超声心动图检查患者653例,并对所有患者分组:正常对照组和主动脉瓣钙化组(左冠瓣钙化、右冠瓣钙化,主动脉瓣多瓣膜钙化),对比研究主动脉瓣钙化组与正常对照组间冠心病发病率差异,同时比较单瓣主动脉瓣钙化与冠状动脉狭窄是否发生于同侧。结果主动脉瓣钙化组冠心病的检出率明显高于正常对照组,单瓣主动脉瓣钙化与同侧冠脉狭窄无明显相关性。结论主动脉瓣钙化患者有更高的冠心病发病率,主动脉瓣钙化可以作为冠心病无创评估的一个参考指标。

Objective To explore the relationship between the aortic valve calcification （ AVC ） and coronary artery disease（CAD）. Methods Six hundred and fifty-three patients underwent transthoracic echocardiography and coronary arteriography at the same time were analyzed retro-spectively in the study. All patients were divided into two groups： normal control group and aortic valve calcification group （left valve calcification, right valve calcification, multiple aortic valve calcification）, comparison of the incidence of coronary artery disease between aortic valve calcification group and normal control group. Analysis of the correlation between single aortic valve calcification and coronary artery stenosis. Results The incidence of coronary artery disease aortic in AVC group was markedly higher than in normal control group. There was no obvious correlation between single aortic valve calcification and the same side coronary artery stenosis. Conclusion Patients with aortic valve calcification have a higher incidence of coronary artery disease, aortic valve calcification can be used as a reference index of noninvasive assessment of coronary artery disease.