血清孕酮水平检测对早期妊娠不良结局的预测价值

THE PREDICTIVE VALUE OF SERUM PROGESTERONE LEVELS IN THE EARLY DETECTIVE OF ADVERSE PREGNANCY OUTCOME IN ANALYSIS

目的对测定孕4—8周早期妊娠者血清孕酮水平展开分析，探讨血清孕酮水平检测对早期妊娠不良结局的预测价值。方法随机选取2011年1月-2012年12月期间我院收治的565例早期妊娠妇女，行血清孕酮水平化学发光检测，结合动态检测血孕酮水平以及B超结果，追踪其妊娠结局，根据其妊娠结局分为3组：先兆流产组（追踪至孕12周安胎成功）319例，稽留流产组（追踪至确诊胚胎停止发育的宫内孕）136例，异位妊娠组（追踪至确诊为宫外妊娠）110例，对其临床数据展开回顾性分析。结果先兆流产组和稽留流产组血清孕酮水平对比，先兆流产组血清孕酮值显著高于稽留流产组，差异具有统计学意义（p〈0．05）。先兆流产组和异位妊娠组血清孕酮水平对比，先兆流产组血清孕酮值显著高于异位妊娠组，差异具有统计学意义（p〈0．01）。结论早期妊娠者的血清孕酮水平检测对其妊娠不良结局有着较好的预测价值，临床上值得广泛推广。

Objective To determine at 4 to 8 weeks early pregnancies serum progesterone level analysis, to explore serum progesterone level detection of predictive value for early adverse pregnancy outcomes. Methods Randomly selected in January 2011 -565 cases in our hospital during early December 2012 pregnant women, serum progesterone levels line chemiluminescence detection, combined detection of serum progesterone levels and dynamic B - results, track their pregnancy outcome, according to their pregnancy outcomes were divided into three groups： threatened abortion （miscarriage 12 weeks pregnant track to success） 319 cases, missed abortion （trace to stop development of the embryo confirmed intrauterine pregnancy） 136 cases of ectopic pregnancy （diagnosed track to Palace outside of pregnancy） 110 cases, expand their clinical data were retrospectively analyzed. Results Missed abortion threatened abortion group and comparison of serum progesterone levels, serum progesterone values were significantly higher than those of threatened abortion missed abortion group, the difference was statistically significant （p 〈 0. 05 ）. Threatened abortion group and the comparison group of ectopic pregnancy serum progesterone levels, serum progesterone threatened abortion group was significantly higher than the ectopic pregnancy group, the difference was statistically significant （p 〈 0. 01 ）. Conclusion Serum progesterone levels early pregnancy testing its poor pregnancy outcomes has a better predictive value, worth clinically widely.