个性化健康教育联合重复经颅磁刺激对帕金森病患者抑郁焦虑的干预

Influence of individualized health education in combination with repetitive transcranial magnetic stimulation on depression and anxiety in patients with Parkinson＇s disease

目的 探讨个性化健康教育联合重复经颅磁刺激对帕金森病患者抑郁焦虑心理的影响,为加强对帕金森病的治疗提供临床参考.方法 抽取我院2011年4月份到2013年6月份收治的80例帕金森病伴焦虑抑郁患者作为研究对象,按照随机分组的方式分为对照组和观察组,每组40例,在抗帕金森病药物治疗方案不变的前提下,对照组采用重复经颅磁刺激干预,观察组在此基础上加用个性化健康教育干预,选择抑郁自评量表（SDS）与焦虑自评量表（SAS）对两组的抑郁焦虑情绪评估,对治疗前后的得分进行分析和比较.结果 经研究发现,两组治疗后的SDS、SAS评分均有不同程度的改善在治疗后的3周、3个月后,观察组的SDS分别为（49.1±3.2）分、（46.8±1.8）分,SAS分别为（47.1±3.3）分、（46.3±2.2）分,与对照组SDS的（53.5±3.1）分、（52.6±1.6）分和SAS的（49.7±3.6）分、（50.5±3.7）分比较,差异有统计学意义（P＜0.05）.结论 给予帕金森病患者个性化健康教育联合重复经颅磁刺激进行治疗,能够在保证临床整体治疗效果的同时,有效缓解和减轻患者的抑郁、焦虑心理,提高生活质量,具有较高的临床应用价值,值得进一步推广.

Objective To study the influence of individualized health education in combination with repetitive transcranial magnetic stimulation on depression and anxiety in patients with Parkinson＇s disease and to provide some references for treating of Parkinson＇s disease.Methods 80 patients with Parkinson＇s disease complicated with anxiety and depression were selected from our hospital from April,2011 to June,2013 as study objects and were randomly divided into a control group and an observation group,40 cases for each group.The control group adopted repetitive transcranial magnetic stimulation intervention; in addition,the observation group received individualized health education.Depression self rating scale （SDS） and anxiety self rating scale （SAS） were used to assess the anxiety and depression of both groups＇ patients.The scores were analyzed and compared before and after treatment.Results After the treatment,SDS and SAS scores were improved in different degrees in both groups.3 weeks and 3 months after the treatment,the SDS scores were （49.1 ± 3.2） and （46.8 ± 1.8） and the SAS scores were （47.1 ± 3.3） and （46.3 ± 2.2） in the observation group and the SDS were （53.5 ± 3.1） and （52.6 ± 1.6） and the SAS scores were （49.7 ± 3.6） and （50.5 ± 3.7） in the control group,respectively,with statistical differences （P〈0.05）.Conclusions Individualized health education in combination with repetitive transcranial magnetic stimulation for patients with Parkinson＇s disease is effective,can reduce the patients＇ depression and anxiety and improve their quality of life,has high clinical value,and is worth being generalized.