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阿托伐他汀治疗冠状动脉旁路移植术后心房颤动的疗效观察 被引量：2

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摘要 目的观察阿托伐他汀治疗冠状动脉旁路移植(CABG)术后心房颤动(AF)的疗效。方法选取2008年1月-2012年6月收治并行CABG手术的患者90例按随机、自愿原则分为对照组和观察组各45例。观察组术前1周开始口服阿托伐他汀10mg/d,对照组不给予阿托伐他汀治疗,对患者进行连续7d的心电监护,记录AF的发生情况。检测术前和术后7d 2组患者高敏C-反应蛋白(hs-CRP)的水平。结果观察组术后AF发生率为15.6%明显低于对照组的35.6%,差异有统计学意义(P<0.05);观察组AF持续时间和最快心室率明显小于对照组,差异均有统计学意义(P<0.05);而2组间术后AF起始时间差异无统计学意义(P>0.05)。2组间术前hs-CRP差异无统计学意义(P>0.05),而观察组术后7d的hs-CRP明显低于对照组,差异有有统计学意义(P<0.05)。结论阿托伐他汀可以减轻CABG术后的炎性反应程度,降低术后房颤的发生率。
作者 花光斌 朱国玺 李立明 杨蓓红
机构地区 河南煤化焦煤集团中央医院心胸外科
出处 《临床合理用药杂志》 2014年第17期53-54,共2页 Chinese Journal of Clinical Rational Drug Use
关键词 冠状动脉旁路移植 阿托伐他汀 心房颤动 炎性反应
分类号 R654.2 [医药卫生—外科学]
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参考文献5

二级参考文献50

  • 1王前,郑磊,曾方银.超敏C-反应蛋白的研究现状及临床应用[J].中华检验医学杂志,2004,27(8):542-544. 被引量：193
  • 2汪斌,刘志忠,张丰富.冠状动脉介入诊治中高敏C反应蛋白与造影剂肾病的相关性分析[J].中国医药,2007,2(8):457-459. 被引量：35
  • 3庄庭怡,毛静远.冠心病心绞痛与肿瘤坏死因子-α、白介素-1β及白介素-6关系的研究概况[J].中国心血管病研究,2007,5(8):613-615. 被引量：26
  • 4Echahidi N, Pibarot P, OHara G, et al. Mechanisms, prevention and treatment of atrial fibrillation after cardiac surgery. J Am Coll Cardiol, 2008, 51: 793-801.
  • 5Mathew JP, Fontes ML, Tudor IC, et al. A multicenter risk index for atrial fibrillation after cardiac surgery. JAMA, 2004, 291: 1720-1729.
  • 6Hogue CW Jr, Creswell LL, Gutterman DD, et al. Epidemiology, mechanisms, and risks: American College of Chest Physicians guidelines for the prevention and management of postoperative atrial fibrillation after cardiac surgery. Chest, 2005, 128 : 9S- 16S.
  • 7Villareal RP, Hariharan R, Liu BC, et al. Postoperative atrial fibrillation and mortality after coronary artery bypass surgery. J Am Coll Cardiol, 2004, 43: 742-748.
  • 8Paterl P, Dokainish H, Tsai P, et al. Update on the association of inflammation and atrial fibrillation. J Cardiovasc Electrophysiol, 2010, 21 : 1064-1070.
  • 9Hogue CW Jr,Palin CA, Kailasam R, et al. C-reactive protein levels and atrial fibrillation after cardiac surgery in women. Ann Thorae Surg, 2006, 82: 97-102.
  • 10Masson S, Aleksova A, Favero C, et al. Predicting atrial fibrillation recurrence with circulating inflammatory markers in patients in sinus rhythm at high risk for atrial fibrillation: data from the GISSI atrial fibrillation trial. Heart, 2010, 96: 1909-1914.

共引文献22

同被引文献20

  • 1Alejandro R. Jadad,R.Andrew Moore,Dawn Carroll,Crispin Jenkinson,D.John M. Reynolds,David J. Gavaghan,Henry J. McQuay.Assessing the quality of reports of randomized clinical trials: Is blinding necessary?[J]. Controlled Clinical Trials . 1996 (1)
  • 2Laurent Fauchier,Bertrand Pierre,Axel de Labriolle,Caroline Grimard,Noura Zannad,Dominique Babuty.Antiarrhythmic Effect of Statin Therapy and Atrial Fibrillation[J]. Journal of the American College of Cardiology . 2008 (8)
  • 3David L. Turpin.??CONSORT and QUOROM guidelines for reporting randomized clinical trials and systematic reviews(J)American Journal of Orthodontics & Dentofacial Orthopedics . 2005 (6)
  • 4Giuseppe Patti,Massimo Chello,Dario Candura,Vincenzo Pasceri,Andrea D’Ambrosio,Elvio Covino,Germano Di Sciascio.??Randomized Trial of Atorvastatin for Reduction of Postoperative Atrial Fibrillation in Patients Undergoing Cardiac Surgery: Results of the ARMYDA-3 (Atorvastatin for Reduction of MYocardial Dysrhythmia After cardiac surgery) Study(J)Circulation . 2006 (14)
  • 5Ronnier J. Aviles,David O. Martin,Carolyn Apperson-Hansen,Penny L. Houghtaling,Pentti Rautaharju,Richard A. Kronmal,Russell P. Tracy,David R. Van Wagoner,Bruce M. Psaty,Michael S. Lauer,Mina K. Chung.??Inflammation as a Risk Factor for Atrial Fibrillation(J)Circulation: Journal of the American Heart Association . 2003 (24)
  • 6Ji Qiang,Mei Yunqing,Wang Xisheng,Sun Yifeng,Feng Jing,Cai Jianzhi,Xie Shiliang,Chi Liangjie.Effect of preoperative atorvastatin therapy on atrial fibrillation following off-pump coronary artery bypass grafting. Circulation journal : official journal of the Japanese Circulation Society . 2009
  • 7Hu YF,Chen YJ,Lin YJ,et al.Inflammation and the pathogenesis of atrial fibrillation. Nat Rev Cardiol . 2015
  • 8Maria Luisa Loricchio,Cinzia Cianfrocca,Vincenzo Pasceri,Leopoldo Bianconi,Antonio Auriti,Leonardo Calo,Filippo Lamberti,Antonio Castro,Claudio Pandozi,Antonio Palamara,Massimo Santini.??Relation of C-Reactive Protein to Long-Term Risk of Recurrence of Atrial Fibrillation After Electrical Cardioversion(J)The American Journal of Cardiology . 2007 (10)
  • 9Yinong Young-Xu,Samer Jabbour,Robert Goldberg,Charles M Blatt,Thomas Graboys,Brian Bilchik,Shmuel Ravid.??Usefulness of statin drugs in protecting against atrial fibrillation in patients with coronary artery disease(J)The American Journal of Cardiology . 2003 (12)
  • 10DEHGHANI MR,KASIANZADEH M,REZAEI Y,et al.Atorvastatin reduces the incidence of postoperative atrial fibrillation in statin-naive patients undergoing isolated heart valve surgery:a double-blind,placebo-controlled randomized trial. J CARDIOVASC PHARM T . 2015

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二级引证文献5

临床合理用药杂志
2014年 第17期

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