二维脉冲多普勒对健康人初到高原心功能的评价

ASSESSMENT OF CARDIAC FUNCTION BY TWO DIMENSIONAL DOPPEER ECHOCARDIOGRAPHY IN 100 HEALTHY NEWCOMERS TO HIGH ALTITUDE

本文采用二维脉冲多普勒超声心动图仪记录了100例健康人由平原陆运到高原前后心脏各瓣口血流变化。其结果，进藏后主动脉瓣口血流速度比进藏前显著增快，而射血时间缩短；计算其每搏流速 积分无显著差异；由于进藏后心率明显增快，故每分输出量明显增加，二尖瓣口和三尖瓣口血流E峰速 进藏后明显减低，A/E比值明显增大，表明心脏舒张功能障碍，此外，肺动脉瓣口血流进藏后比进藏前加速时间明显缩短，减速 时间明显，证明初到高原即可出现肺动脉高压。

The trans-valvular blood flow velocities and cardiac output were studied with two dimensional Doppler echocardiography in 100 recruits before and after a journey by land from sea level to high altitude. The results showed that after the journey to high altitude, the peak velocity (PV) at aortic valve orifice was increased, the ejection time was shortened and there was no significant change in integrated stroke velocity. Cardiac output was much higher after the journey. This attributed mainly to the increased heart rate. In addittion, the peak E of mitral and tricuspid valve fiow velocities were decreased, and the A / E ratios were increased correspondingly after the journey. These observations indicated that cardiac diastolic disfunction may occur within a few days after the arrival to high altitude. Moreover, PV at pulmonary valve orifice was increased, the flow velocity acceleration time was shortened and the deceleration time was prolonged after the journey. These changes demonstrated that healthy newcomers to high altitude may soon be afflicted with an increased pulmonary pressure.