四逆散加味联合西药治疗寒热错杂型功能性消化不良的临床疗效观察

Clinical Efficacy of Sini Powder and Western Medicine in the Treatment of Mixed Cold and Heat Functional Dyspepsia

目的:探究四逆散加味治疗对功能性胃肠病的临床疗效。方法:94例功能性胃肠病患者依照随机数字表法分为观察组和对照组。每组各47例。对照组接受心理治疗和饮食控制,吗丁啉片,每天3次,每次10mg,疗程为1个月。观察组在对照组的基础上接受四逆散加减方。结果:对照组的显效为18例,有效为14例,总有效率68.1%。观察组的显效25例,有效为19例,总有效率89.4%。观察组中总有效率高于对照组的总有效率,差异明显具有统计学意义(χ2=6.51,P<0.05)。在治疗过程中,对照组复发有9例,复发率为28.1%,观察组复发有3例,复发率为7.1%,两组复发率比较具有明显差异(χ2=6.51,P<0.01)。结论:四逆散加味联合西药治疗寒热错杂型功能性胃肠病的临床疗效显著,复发率低、不良反应少。

Objective：To investigate the clinical efficacy of Sini powder combined with western medicine on mixed cold and heat functional dyspepsia .Methods： 94 cases of patients with functional gastrointestinal dyspepsia in accordance with random number table were divided into an observation group and a control group .There were 47 cases in each group .The control group was received psychological treatment and diet control .The control group was given domperi-done tablets of 10mg three times daily.This treatment lasted for a month .The observation group was received Sini pow-der on the basis of the therapy in the control group .Results： In the control group 18 cases showed markedly effective-ness.14 cases showed effectiveness .The rate of total efficiency was 68.1%.In the observation group 25 cases showed markedly effectiveness .19 cases had effectiveness .The total efficiency was 89 .4%.In the observation group the total efficiency was better than that in the control group and it had significant differences （χ^2 =6.51,P〈0.05）.During treatment , control group had nine cases of recurrence .The recurrence rate was 28 .1%;observation group had three ca-ses of recurrence.The recurrence rate was 7.1%.The relapse rate between the two groups had a significant difference （χ^2 =6.51,P〈0.01）.Conclusion： Sini powder combined with western medicine in the treatment of mixed cold and heat functional dyspepsia have a significantly efficacy , lower recurrence rate and no adverse reactions .