中药冲洗胆道介入治疗急性梗阻性化脓性胆管炎临床疗效观察

Clinical Efficacy of Suppurative Therapy of Chinese Medicine Rinsing Biliary on Acute Obstructive Suppurative Cholangitis

目的:探究中药冲洗胆道介入治疗急性梗阻性化脓性胆管炎临床疗效。方法:84例急性梗阻性化脓性胆管炎患者随机分为观察组和对照组,每组各42例。两组患者都接受常规治疗和ENBD手术,术后观察组用茵陈蒿注射液联合抗生素冲洗,对照组只采用抗生素冲洗,手术后比较胆总管内径、血清总胆红素和肝功能。结果:手术3天后无腹痛现象。两组患者的体温、黄疸指数、临床症状和体征都改善或者消失。两组手术后胆总管内径缩小,碱性磷酸酶、谷-丙转氨酶和总胆红素下降,观察组的总胆红素、谷-丙转氨酶改善值优于对照组(t=8.12,6.87,P<0.05)。结论:中药冲洗胆道介入治疗急性梗阻性化脓性胆管炎可以有效改善总胆红素和谷-丙转氨酶水平,效果优于单用抗生素冲洗。

Objective：To explore the clinical efficacy of interventional Chinese medicine on acute obstructive cholangitis . Methods：84 patients with acute obstructive suppurative cholangitis were divided into observation group and control group randomly .There were 42 cases in each group .Patients in two groups received conventional treatment and ENBD surgery . The observation group was given tarragon injection and antibiotics rinsing biliary .The control group was given antibiotic rinsing biliary .Then duct diameter , serum total bilirubin and liver function were compared after surgery .Results：Pa-tients had no pain after surgery .Body temperature , jaundice index , and clinical symptoms in two groups were improved or disappeared .After surgery the diameter of bile duct was narrowed .Alkaline phosphatase , Valley -alanine amin-otransferase and total bilirubin were decreased .The change of total bilirubin , the valley-pyruvic transaminase in the observation group were better than those in the control group （t=8.12,6.87,P〈0.05）.Conclusion：Chinese medicine rinsing biliary on acute obstructive suppurative cholangitis can effectively decease the level of total bilirubin and valleys-pyruvic transaminase .The effect is better than single antibiotic rinse .