奥拉西坦治疗46例脑梗死后遗症的疗效观察

Clinical observation on oxiracetam in the treatment of 46 cases of cerebral infarction sequelae

目的观察奥拉西坦治疗46例脑梗死后遗症的疗效。方法 46例脑梗死后遗症患者,作为治疗组;再选取同一个时间段内的46例脑梗死后遗症患者,作为对照组;对照组用长春西汀和血栓通(或丹红),14 d为1疗程;治疗组在对照组的基础上加用奥拉西坦,疗程14 d。治疗前、后对两组的治疗结果进行巴氏指数和神经功能缺损评分。结果治疗后治疗组神经功能缺损程度评分为(10.5±3.1)分、巴氏指数评分为(96.1±8.3)分较对照组有明显改善比较差异有统计学意义(P<0.05)。结论奥拉西坦在治疗脑梗死后遗症方面的疗效显著。

Objective To observe effect of oxiracetam in the treatment of 46 cases of cerebral infarction sequelae. Methods Selected 46 patients with cerebral infarction sequela as treatment group; selected same period 46 patients with cerebral infarction sequela as control group. Control group was treated with vinpocetine, thrombus（or Dangong）, 14 days as a course; treatment group on the basis of control group added olathe, 14 days as a course, pap index and neural function defect scale were performed before and after treatment. Results Barthel index and neural function defect scale of treatment group were （10.5 ± 3.1）, （96.1 ± 8.3） respectively, which was obviously improved compared with control group, differences had statistical significance（P〈0.05）. Conclusion Oxiracetam in the treatment of cerebral infarction sequelae has a remarkable curative effect.