强离子隙在急性心肌梗死中的临床意义

Clinical Significance of SIG in Patients with Acute Myocardial Infarction

【目的】探讨强离子隙（SIG）在急性心肌梗死（AMI）中的临床意义。【方法】对2010年3月至2012年9月本院治疗的83例 AMI患者，应用 Stewart-Figge方法计算其血气分析结果，并进行比较分析。【结果】治疗有效组中 SIG、阴离子隙（AG）、潜在碳酸氢根（pHCO3-）等指标明显低于治疗无效组，且都具有统计学意义（P ＜0．05），其中 SIG的变化幅度最大，AG次之，pHCO3-变化最小。【结论】在 AMI患者中，SIG可以比 AG和潜在HCO3-能更好地反映患者体内酸碱平衡情况，对于病情的检测和短期预后评估有着重要的临床价值。

[Objective]To explore clinical significance of strong ion gap（SIG）in patients with acute myocardial in-farction（AMI）.[Methods]Stewart-Figge methodology was used to calculate,compare and analyze the results of blood gas analysis of 83 patients with AMI in our hospital from March 2010 to Sept.2012.[Results]The indexes such as SIG, AG and potential HCO3- in effective treatment group were obviously lower than those in ineffective treatment group,and there was significant difference（P〈0.05）Among the indexes,the change of SIG was the biggest,and that of AG was the second,and that of potential HCO3- was the smallest[Conclusion]In AMI patients,SIG can better reflect acid-base balance of AMI patients than AG and potential HCO3-,and has important clinical value in the detection of illness state and the assessment of short-time prognosis.