摘要
目的:观察药物结合乒乓球运动对老年性痴呆(AD)患者的影响。方法:将100例AD患者随机分为观察组和对照组,对照组患者给予叶酸10 mg,维生素B12 500μg,每日1次。观察组患者在对照组治疗基础上每隔1日增加1小时乒乓球运动。1年后对所有患者进行简易智力状态量表(MMSE)和日常生活活动能力量表(ADL)测定,同时检测患者尿中甲醛和神经丝蛋白(AD7c-NTP)的含量。结果:与对照组比较,治疗后观察组整体疗效明显优于对照组(P<0.05);MMSE评分有显著性差异(P<0.05);尿中甲醛和AD7c-NTP含量差异有统计学意义(P<0.05)。结论:在补充叶酸、维生素B12的基础上结合乒乓球运动对AD患者的防治及生活自理能力有明显改善。
Objective: To observe the effect of medicine in combination with table tennis on Alzheimer' s Disease (AD) patients. Methods: 100 cases of AD patients were randomly divided into observation group and control group, the control group played table tennis up to 1 hour were treated with folio acid and vitamin 10mg, B12 500μg, once a day. Patients in the observation group based on the treatment in control group every other day. After 1 year for all patients with Mini Mental State Scale (MMSE) and activities of daily living scale (ADL) were measured at the same time, detection of formaldehyde and neurofilament protein ( AD7c - NTP) in urine of patients with content. Results : Compared with the control group, after treatment, the overall effect of observation group was superior to that of control group ( P 〈 0. 05 ) ; MMSE score had significant difference (P 〈 0.05 ) ; there was significant difference of formaldehyde and AD7c - NTP content in urine ( P 〈0. 05). Conclusion: On the basis of folio acid, vitamin B12 combined with prevention with table tennis, self - care ability of seniles with AD is improved obviously.
出处
《山东体育科技》
北大核心
2014年第3期108-110,共3页
Shandong Sports Science & Technology
基金
国家自然科学基金(编号:30672114)
山西省自然科学基金(编号:20090110571)