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透明质酸在肿瘤治疗药物新型给药系统中的应用 被引量:5

Application of hyaluronic acid in the novel drug delivery system for cancer therapy
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摘要 透明质酸(hyaluronic acid,HA)因其良好的理化性质和肿瘤靶向性,已作为药物载体或者靶向因子应用于肿瘤治疗的新型给药系统中,并成为肿瘤治疗研究的热点。本文主要对HA在新型给药系统的应用进行介绍。 Due to the good physical and chemical properties and tumor targeting ability, hyaluronic acid (HA) has been used as drug carriers or targeting ligand in the novel drug delivery system for cancer therapy, and become the new hot point in the field of cancer therapy. This review mainly introduced the application of HA in the novel drug delivery system.
出处 《中国实用医药》 2014年第16期238-241,共4页 China Practical Medicine
关键词 透明质酸 肿瘤靶向 纳米粒 胶束 脂质体 自组装复合物 Hyaluronic acid Tumor targeting Nanoparticles Micells Liposome Self-assembled complex
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  • 1Orian-Rousseau V. CD44, a therapeutic target for metastasising tumours.Eur J Cancer, 2010,46(7): 1271 - 1277.
  • 2Ossipov DA. Nanostructured hyaluronic acid-based materials for active delivery to cancer.Expert Opin Drug Deliv, 2010,7(6):681- 703.
  • 3Yun YH, Goetz DJ, Yellen P, Chen W. Hyaluronan mierospheres for sustained gene delivery and site-specific targeting. Biomaterials. 2004,25(1): 147-157.
  • 4Pitarresi G, Craparo EF, Palumbo FS, et al. Composite nanopartieles based on hyaluronic acid chemically cross-linked with alpha,beta- polyaspartylhydrazide. Biomaeromoleeules ,2007,8(6): 1890-1898.
  • 5Lee H, Mok H, Lee S, et al. Target-specific intraeellular delivery of siRNA using degradable hyaluronic acid nanogels. J Control Release, 2007, 119(2):245-252.
  • 6De la Fuente M, Seijo B, Alonso MJ. Bioadhesive hyaluronan- chitosan nanoparticles can transport genes across the ocular mucosa and transfect ocular tissue. Gene Ther ,2008,15(9):668-676.
  • 7De la Fuente M, Seijo B, Alonso MJ. Design of novel polysaccharidie nanostructures for gene delivery. Nanotechnology, 2008,19(7):1-9.
  • 8Nasti A, Zaki NM, de Leonardis P, et al. Chitosan/IPP and ehitosan/ TPP-hyaluronic acid nanoparticles: systematic optimisation of the preparative process and preliminary biological evaluation. Pharm Res, 2009,26(8): 1918-1930.
  • 9Yang XY, Li YX, Li M, et al. Hyaluronie acid-coated nanostructured lipid carriers for targeting paclitaxel to cancer. Cancer Lett, 2013, 334(2):338-345.
  • 10Vangara KK, Liu JL, Palakurthi S. Hyaluronie acid-decorated PLGA-PEG nanoparticles for targeted delivery of SN-38 to ovariancaneer.Anticaneer Res. 2013,33(6):2425-2434.

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