临床药师对心脏介入手术围手术期预防用抗菌药的干预效果

Effect Evaluation of Clinical Pharmacist Intervention on Perioperative Preventive Use of Antibiotics in Patients Undergoing Cardiac Intervention Surgery

目的：评价临床药师干预心脏介入手术围手术期预防用抗菌药的效果.方法：临床药师分两步制定干预措施,督促落实.对干预前（2011年）及干预后（2012年、2013年1～6月）心脏介入手术预防用抗菌药的情况进行比较研究.结果：临床药师干预后,诊断性介入造影术和冠脉支架置入术的预防用药率分别由干预前的90.72％、99.07％下降至0,永久起搏器植入术的预防用药时间由干预前的3d以上缩至为1d,差异均有统计学意义（P＜0.01）.结论：临床药师有效地促进了心脏介入手术围手术期抗菌药的合理使用.

Objective：To evaluate the intervention effect of clinical pharmacists on the perioperative preventive use of antibiotics in the patients undergoing cardiac intervention surgery.Methods：The clinical pharmacists carried out the intervention measures by two steps,and supervised the implementation.The patients undergoing cardiac intervention surgery in 2011 （before the intervention）,2012 （after the first step of intervention）,and from January to June of 2013 （after the second step intervention）were collected and compared.Results：Due to the intervention of clinical pharmacists,the prophylactic application rate of antibiotics in CAG and PCI operation was significantly decreased from 90.72% and 99.07% to 0.The course of preventive medication treatment in permanent cardiac pacemaker implantation was significantly decreased from more than 3 days to 1 day （P 〈0.01）.Conclusion：The intervention measures taken by clinical pharmacists on the perioperative preventive use of antibiotics in patients undergoing cardiac intervention surgery are very effective.