6Cabhno L A, Han G Y. The 9 - fluorenylmethoxycarbonyl function, a new base - sensitive amino protecting group [J]. J Am Chem,Soc, 1970, 92(5) : 748 -750.
7Stephen Bergmeier. The synthesis of vicinal amino alcohols [J]. Tetrahedron, 2000, 56:2561 -2576.
8Nicholas G M, Hong T W, Molinski T F. Oceanapiside, an antifungal bis - ct, w - amino alcohol glycoside from the ma- rine sponge oceanapia phiUipensis [ J ]. J Nat Prod, 1999, 62(12) : 1678 - 1681.
2Pitson SM, Moretti PA, Zebol JR,et al.Activation of sphingosine kinase 1 by ERK1/2-mediated phosphorylation[J].EMBO J, 2003,22(20): 5491-5500.
3Gulbins E. Regulation of death receptor signaling and apoptosis by ceramide[J].Pharmacol Res, 2003,47(5): 393-399.
4Ohta H, Yatomi Y, Sweeney EA, et al. A possible role of sphingosine in induction of apoptosis by tumor necrosis factor-alpha in human neutrophils[J].FEBS Lett, 1994,355(3): 267-270.
5Cuvillier O, Pirianov G, Kleuser B, et al. Suppression of ceramide-mediated programmed cell death by sphingosine-1-phosphate[J].Nature, 1996,381(6585): 800-803.
6Chang HC, Hsu C, Hsu HK, et al. Functional role of caspases in sphingosine-induced apoptosis in human hepatoma cells[J].IUBMB Life,2003,55(7): 403-407.
7Nakamura H, Oda T, Hamada K, et al. Survival by Mac-1-mediated adherence and anoikis in phorbol ester-treated HL-60 cells[J].J Biol Chem, 1998,273(25): 15345-15351.
8Kohama T, Olivera A, Edsall L, et al. Molecular cloning and functional characterization of murine sphingosine kinase[J].J Biol Chem, 1998, 273(37): 23722-23728.
9Nava VE, Lacana E, Poulton S,et al.Functional characterization of human sphingosine kinase-1[J].FEBS Lett, 2000, 473(1): 81-84.
10Pitson SM, D'andrea RJ, Vandeleur L,et al.Human sphingosine kinase: purification, molecular cloning and characterization of the native and recombinant enzymes[J].Biochem J, 2000,350 (2): 429-441.