银杏达莫注射液治疗慢性肺源性心脏病56例

Ginkgo Leaf Extract and Dipyridamole Injection in Treating 56 Cases of Chronic Pulmonary Heart Disease

目的:观察银杏达莫注射液治疗慢性肺源性心脏病(失代偿期)的临床疗效。方法:将112例患者随机分为2组,每组56例,对照组采取抗感染、祛痰、持续低流量吸氧、解痉平喘、防治并发症等常规治疗,治疗组同时使用银杏达莫注射液20 mL+0.9%氯化钠注射液250 mL静脉滴注,1次/d。治疗10天后对比2组临床疗效、血液流变学及B型尿钠肽(BNP)指标。结果:2组治疗后临床症状及体征均有改善(P<0.05),但治疗组的改善程度明显优于对照组(P<0.05);治疗组血液流变学及BNP指标下降程度优于对照组(P<0.05)。结论:银杏达莫注射液治疗慢性肺源性心脏病临床疗效显著,可改善心肺功能,降低血液黏度。

Objective：To observe therapeutic effects of ginkgo leaf extract and dipyridamole injection in treat-ing chronic pulmonary heart disease （discompensation stage）. Methods：All 112 patients were randomized into two group, 56 cases each group, the control group received routine treatment of anti-inflammation, dispelling the phlegm, continnus low flow rate oxygen inhalation, relieving the spasm and the asthma, preventing the complications, the treatment group accepted intravenous dripping of ginkgo leaf extract and dipyridamole injection, 20 mL, and 0.9%sodium chloride injection, 250 mL, once per day. B-type natriuretic peptide （BNP）, blood rheology and curative ef-fects of both groups were compared after treating for ten days. Results：Clinical symptoms and body signs of both groups were improved （P〈0.05）, but the improvement of the treatment group was superior to that of the control group obviously （P〈0.05）;the decreases of blood rheology and BNP in the treatment group were superior to these of the control group （P〈0.05）. Conclusion：Ginkgo leaf extract and dipyridamole injection in treating chronic pul-monary heart disease could gain better effects in clinic, the injection could improve heart and pulmonary function, decrease blood viscosity.