高压氧综合治疗心肺复苏术后意识障碍患者的疗效观察

Clinical effects of combined hyperbaric oxygen in the treatment of unconscious patients after cardiopulmonary resuscitation

目的 评估高压氧综合治疗心肺复苏后意识障碍患者的疗效,分析高压氧治疗心肺复苏后意识障碍中相关因素与疗效的关系.方法 回顾2002-2012年我科应用高压氧综合治疗心肺复苏术后意识障碍患者33例,对发病年龄、发病原因、高压氧治疗次数、高压氧治疗时机与疗效的关系进行分析.结果 高压氧综合治疗非心源性疾病效果明显优于心源性疾病（P＜0.05）,开始治疗时间≤30 d治疗效果明显好于＞30 d开始治疗的效果（P＜0.05）,患者年龄≤35岁治疗效果明显好于≥36岁患者（P＜0.05）.结论 心肺复苏后意识障碍患者高压氧综合治疗的效果与年龄、病因、高压氧开始治疗的时间有关,年轻、非心源性疾病、高压氧开始治疗时间早（≤30 d）的患者治疗效果较好.

Objective To assess the therapeutic effects of combined hyperbaric oxygen （HBO） in the treatment of unconscious patients after cardiopulmonary resuscitation and also to analyze the relationship between factors associated with HBO in the treatment of conscious disorder and therapeutic effects after cardiopulmonary resuscitation.Methods A retrospective analysis was made on the effects of combined HBO in the treatment of 33 cases of conscious disorder following cardiopulmonary resuscitation from 2002-2012.Patient age,pathogenic factors,courses of HBO treatment and the relationship between treatment time and therapeutic effects were analyzed systematically.Results The effect of comprehensive HBO in the treatment of non-cardiac diseases was obviously superior to that of cardiac diseases（P ＜ 0.05）.The therapeutic effect of early treatment （less than 30 days） was obviously better than that of delayed treatment （more than 30 days） （P ＜ 0.05）,and patients with a junior age （less than 35 years old） obviously had better therapeutic effects than those with senior age （more than 36 years old） （P ＜ 0.05）.Conclusions The therapeutic effect of HBO in the treatment of unconscious patients after cardiopulmonary resuscitation was closely associated with the age,etiology and starting time of HBO therapy.Patients with younger age and non-cardiac diseases and receiving early HBO therapy could achieve better results.