阿托伐他汀对46例腔隙性脑梗死患者脑血管反应性影响的临床研究被引量：1

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摘要目的观察阿托伐他汀对46例腔隙性脑梗死患者脑血管反应性的影响。方法选择2011年12月至2013年9月接受治疗的腔隙性脑梗死患者46例，按随机数字表法分为观察组和对照组，每组23例。对照组给予常规治疗，而观察组在对照组的基础上加用阿托伐他汀治疗。两组均连续治疗3个月。治疗前后行屏气试验，计算两组患者双侧大脑中动脉（MCA）的屏气指数（BHI）和平静呼吸时MCA平均血流速度（Vr）。结果两组治疗前双侧MCA的BHI比较差异无统计学意义（P〉0．05）。治疗后观察组左、右侧MCA的BHI分别为1．47±0．38和1.51±0．35，对照组分别为1．32±0．34和1．35±0．38，观察组治疗后双侧MCA的BHI均明显大于对照组，差异有统计学意义（P〈0．05）。两组治疗前后双侧Vr比较差异均无统计学意义（P〉0．05）。结论阿托伐他汀能显著改善腔隙性脑梗死患者的脑血管反应性，且不影响患者MCA的血流速度和脑血流量。

作者汪飞

机构地区浙江省嘉善县第一人民医院神经内科

出处《中国医师进修杂志》 2014年第18期70-72,共3页 Chinese Journal of Postgraduates of Medicine

关键词脑梗塞阿托伐他汀脑血管反应性

分类号 R743.3 [医药卫生—神经病学与精神病学]

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