壳聚糖抗菌膜用于治疗口腔黏膜创伤的临床疗效观察

CLINICAL EFFECT OF CHITOSAN CERVICAL ANTIBACTERIAL FILM FOR INJURY OF ORAL CAVITY MUCOUS MEMBRANE

目的观察壳聚糖抗菌膜治疗口腔黏膜创伤的临床疗效。方法 108例口腔黏膜创伤的患者随机分成二组,对照组52例含漱西吡氯铵漱口水,4次/d;观察组56例,将壳聚糖抗菌膜喷于黏膜创面表面,4次/d。结果观察组与对照组比较,创口止血时间,疼痛程度及愈合时间,以及总有效率的差异均有统计学意义(P<0.05)。结论壳聚糖抗菌膜对于口腔黏膜创伤的止血、镇痛和促进愈合的效果良好。

Objective To observe the clinical effect of chitosan cervical antibacterial film for injury of oral cavity mucous membrane. Methods A sample of 108 patients was randomly divided into the control group and the treat group. Of 52 patients in the control were treated with cetylpyridinium chloride mouthwash, 4 times/d. Another 56 patients in the treat group were sprayed with the chitosan antibacterial films on the mucosal surface of the injury, 4 times/d. Results There were statistically significant differences （P~ 0.05） among the haemostasis time, pain degree, healing time, and the total effective rate in the two groups. Conclusion The chitosan antibacterial films is good for stanching and analgesia of the oral mucous membrane injury and promoting healing.