扶阳利水法治疗房颤合并心衰疗效观察

Fuyanglishui Decoction Treating 80 Cases with Atrial Fibrillation and Heart failure

目的观察中西医结合治疗方法对房颤合并心功能不全患者的治疗作用及副反应发生情况。方法将80例心房颤动合并舒张性心力衰竭患者随机分成治疗组和对照组,两组患者均给予常规治疗,治疗组加真武汤合苓桂术甘汤,疗程10周。观察两组患者临床症状的有效率,治疗前后心功能指标(心脏超声左室射血分数,左心房内径,舒张期二尖瓣口E峰值、A值,E/A等)以及出现胃肠道反应、电解质紊乱等副反应的发生率。结果治疗组临床症状有效率、心脏超声左室射血分数、左心房内径、舒张期二尖瓣口E峰值、A值,E/A均高于对照组(均P<0.05),C反应蛋白、副反应发生率低于对照组(P<0.05)。结论扶阳利水法联合西药治疗房颤合并心衰的临床疗效优于单纯西药治疗者,且副反应发生率低。

Objective：To explore the effect of combining traditional Chinese and western medicine treating atrial fibrillation with cardiac insufficiency and its incidence of adverse events.Methods：80 cases of atrial fibrillation with diastolic heart failure were randomly divided into treatment group and control group.Two groups of patients were given conventional western medicine treatment.Treatment group on the basis of that was added Zhenwu decoction and Qinguishugan decoction （one dose a day） for 10 weeks.Effective rate,cardiac function index before and after the treatment（echocardiographic left ventricular ejection fraction and left atrial diameter,diastolic mitral valve mouth E peak,A value,E/A,etc.）,and adverse events such as gastrointestinal tract reaction and electrolyte disorders were observed.Results：The effective rate,echocardiographic left ventricular ejection fraction,left atrial diameter,diastolic mitral valve mouth E peak,A value,E/A etc.were higher than those in control group（P＜0.05）.C-reactive protein（CRP） and adverse incidence rate were lower than those in control group （P＜ 0.05）.Conclusion：Fuanglishui decoction combined with western medicine treating atrial fibrillation with heart failure is superior to pure western medicine therapy with lower incidence of side effects than those in control group.