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右美托咪定在经鼻清醒气管插管中的应用

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摘要 目的:观察右美托咪定在清醒经鼻气管插管中应用的临床效果。方法:选择60例患者,随机分为两组:对照组(A组)和右美托咪定组(B组),每组30例。B组在插管前泵注右美托咪定1μg(/kg·h)15min。A组则不泵入。记录并比较插管过程中4个时间点的MAP、HR、SpO2;并观察患者舒适程度,术后随访患者对插管过程的知晓情况。结果:所有患者插管成功,在T2、T3 B组MAP、HR明显低于A组(P<0.05)。两组插管舒适度评分差异有统计学意义(P<0.05),B组明显优于A组。两组患者均未出现对插管过程的知晓。结论:右美托咪定能提高清醒经鼻气管插管时的舒适程度,能显著减轻血流动力学反应,可有效应用于经鼻清醒气管插管。
作者 南晓娟
出处 《北方药学》 2014年第7期44-45,共2页 Journal of North Pharmacy
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