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依那普利联合氨氯地平治疗糖尿病肾病合并高血压的效果分析 被引量:2

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摘要 选取2012年5月-2013年5月我院收治的2型糖尿病患者126例,随机分为观察组及对照组,均采用常规抗糖尿病治疗,降血压治疗和口服氨氯地平,观察组患者在对照组基础上加服依那普利。均治疗12w,并观察治疗效果。结果治疗后,观察组收缩压、舒张压及24h尿蛋白定量分别为127.2±6.5mmHg、81.2±4.5mmHg及0.11±0.02;对照组分别为139.8±7.2mmHg,89.8±5.2mmHg及0.19±0.03。治疗前两组患者各指标差异无统计学意义(P〉0.05)。治疗后两组患者各指标均有所改善,而观察组改善情况优于对照组,且差异具有统计学意义(P〈0.05)。依那普利联合氨氯地平治疗糖尿病肾病合并高血压的临床效果显著。
作者 王翠
机构地区 冕宁县人民医院
出处 《现代诊断与治疗》 CAS 2014年第3期551-552,共2页 Modern Diagnosis and Treatment
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  • 1Leehey DJ, Singh AK, Alavi N. Role of angiotensin Ⅱ in diabetic nephropathy[J]. Kidney Int . 2000,77:93-98.
  • 2Bakris G, White D. Effects of an ACE inhibitor combined with a calcium channel blocker on progression of diabetic nephropa thy[J]. J Hum Hypertens ,1997,11(1):35-38.
  • 3Deray G, Baumelou A, Bagnis C. Amlodipine and long-term renoprotection in hypertensive patients with renal dysfunction [J]. Am J Hypertens ,2001,14(1) :601-602.
  • 4Parving HH, Rossing P. Calcium antagonists and the diabetic hypertensive patient[J]. Am J Kidney Dis ,1993,21(3) :47-52.
  • 5Lehmann R, Schleicher ED. Molecular mechanism of diabetic nephropathy[J]. Clin Chim Acta , 2000,297:1 - 2.
  • 6Nosadini R, Abaterusso C, Dalla Vestra M, et al. Efficacy of antihypertensive therapy in decreasing renal and cardiovascular complications in diabetes mellitus [ J ]. Nephrol Dial Transplant , 1998,13(8) :44-48.
  • 7Bakris GL, Williams B. Angiotensin converting enzyme inhibitors and calcium antagonists alone or combined: does the progression of diabetic renal disease differ[J]. J Hypertens,1995,13(2): 95-101.
  • 8Dworkin LD, Benstein JA, Parker M, et al . Calcium antagonists and converting enzyme inhibitors reduce renal injury by different mechanisms[J]. Kidney Int , 1993,43(4) :808-814.
  • 9Rossing P, Tarnow L, Boelskifte S. Differences between nisoldipine and lisinopril on glomerular filtration rates and albumi nuria in hypertensive IDDM patients with diabetic nephropathy during the first year of treatment[J]. Diabetes , 1997,46 (3):481-487.
  • 10Shultz PJ, Raij L. Effect of amlodipine on mesangial cell pro liferation and protein synthesis[J]. Am J Hypertens , 1992 ,5(1):912-914.

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