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γ干扰素释放试验对活动性结核病诊断价值研究 被引量:1

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摘要 目的探讨γ干扰素释放试验对结核病的诊断价值,为提高结核病诊断技术提供依据支持。方法用上海复兴T-SPOT.TB试剂检测结核和非结核患者外周血单个核细胞,进行γ干扰素释放释放试验,并计数斑点数。结果 TB-IGRA诊断结核病敏感度为0.849,特异度为0.585,假阳性率为0.415,假阴性率为0.151,准确率为0.787。结论 TB-IGRA诊断结核病具有较高的敏感度和特异度,可以作为诊断结核病的较强的辅助技术。
出处 《河北医药》 CAS 2014年第13期1948-1949,共2页 Hebei Medical Journal
基金 国家自然科学基金项目(编号:30873465)
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  • 1Pai M, Denkinger CM, Kik SV, et al. Gamma interferon releaseassays for detection of Mycobaeterium tuberculosisinfection[J]. Clin Microbiol Rev, 2014,27 ( 1 ) : 3-20.
  • 2Sester M, Sotgiu G, Lange C, et al. Interferon-γ release assays for the di- agnosis of active tuberculosis:a systematic review and meta-analysis [J]. Eur Respir J,2011,37 ( 1 ) : 100-111.
  • 3Cattamanchi A,Smith R,Steingart KR,et al. Interferon-gamma release assays for the diagnosis of latent tuberculosis infection in HIV-infected individuals :a systematic review and meta-analysis [J]. J Acquir Immune Defic Syndr, 2011,56 (3) : 230-238.
  • 4Richeldi L,Losi M ,D'Amico R,et al. Performance of tests for latent tu- berculosis in different groups of immunocompromised patients[J]. Chest, 2009,136(1 ) : 198-204.
  • 5Jung JY,Lim JE,Lee HJ,et al. Questionable role of interferon-γ assays for smear-negative pulmonary TB in immunocompromised patients [J]. J Infect,2012,64(2) : 188-196.
  • 6Smith R, Cattamanehi A,Steingart KR. Interferon-γ release assays for di- agnosis of latent tuberculosis infection : evidence in immune-mediated inflammatory disorders[J]. Curr Opin Rheumatol, 2011,23 (4) : 377-384.
  • 7Jones S,de Gijsel D, Wallach FR,et al. Utility of QuantiFERON-TB Gold in-tube testing for latent TB infection in HIV-infected individuals[J]. Int J Tuberc Lung Dis, 2007,11 ( 11 ) : 1190-1195.
  • 8Pavic I ,Topic RZ, Raos M, et al. Interferen-γ release assay for the diag- nosis of latent tuberculosis in children younger than 5 years of age[J]. Pediatr Infect Dis J, 2011,30 (10) : 866-870.
  • 9Bergamini BM, Losi M,Vaienti F, et al. Performance of commercial blood tests for the diagnosis of latent tuberculosis infection in children and ado- lescents[J]. Pediatrics, 2009,123 (3) : e419-424.
  • 10Cruz AT,Marape M,Graviss EA,et at. Performance of the QuantiFERON- TB gold interferon gamma release assay among HIV-infected children in Botswana[J]. J Int Assoc Previd AIDS Care, 2015,14( 1 ) :4-7.

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