摘要
以环戊酮为起始原料,经加成、醇解、缩合、环合反应制得中间体3-(2-甲基苯基)-2-氧代-1-氧杂螺[4,4]-壬-3-烯-4-醇,再与氯代特戊酰氯反应制得HNPC-A9012,总收率大于65%(以环戊酮计),含量大于98%。
With cyclopentanone as the starting raw material, HNPC-A9012 was synthesized via intermediate of 3- (2-methylphenyl)-2-oxo-l-oxaspiro[4,4]-dec-3-ene-4-ol in overall yield of 65% with a purity of 98%.
出处
《精细化工中间体》
CAS
2014年第3期13-15,共3页
Fine Chemical Intermediates
基金
国家"十二五"科技支撑农药项目课题资助(2011BAE06B01)