贡山三尖杉化学成分研究

Studies on the Chemical Constituents of Cephalotaxus lanceolata

从贡山三尖杉枝叶中通过溶剂提取、硅胶柱层析、Sephadex LH-20柱层析、制备薄层层析等方法分得7个化合物。波谱分析（核磁共振氢谱、碳谱和质谱）确定它们的结构分别为11-hydroxyhainanolidol （1）， fortunolide A （2），p-hydroxybenzaldehyde （3），3-methoxy-4-hydroxybenzaldehyde （4），sitosteryl-3β-glucoside-6′-O-palmitate （5），β-sitosterol （6），daucosterol （7），化合物1～5系首次从贡山三尖杉中分离得到。

Seven compounds （1～7 ） were extracted and isolated from the twigs and leaves of Cephalotaxus lanceolata by repeated chromatography.There structures were identified by spectroscopic analysis （^1 H-NMR,^13 C-NMR and EI-MS ）to be 1 1-hydroxyhainanolidol （1 ）,fortunolide A （2 ）,p-hydroxybenzaldehyde （3 ）, 3-methoxy-4-hydroxybenzaldehyde （4 ）, sitosteryl-3β-glucoside-6′-O-palmitate （5）,β-sitosterol （6）,daucosterol （7）.Compounds 1 ~5 were isolated from the plant for the first time.