米索前列醇、阿托品、利多卡因、安定对人工流产术的影响

Mline,atropine,lidocaine on the influence of induced abortion operation

目的观察米索前列醇、利多卡因、阿托品、安定在人工流产术前及术中用于软化宫颈、减轻疼痛,减少出血的临床效果及安全性。方法从2011年12月1日—2012年12月1日来医院接受人工流产的760例妇女中挑选出200例,血或尿HCG测定阳性,B超检查确定为宫内妊娠,均为初次怀孕。孕7-12周并要求终止妊娠者。将其随机分为2组,即观察组与对照组。观察组术前给予患者米索前列醇1片舌下含化,2 h后给患者阴道后穹窿塞1片米索前列醇,然后再给患者安定10 mg静脉推注,30 min后,用阿托品0.5 mg＋2%利多卡因10 ml对患者宫颈进行四点封闭并给予按摩,最后再进行人工流产手术。对照组术前不做任何处理,按常规方法做人工流产手术。结果观察组与对照组比较,手术时子宫颈软化及松弛程度、阴道出血量、手术时间、人工流产综合征发生率,差异均有统计学意义（均P〈0.01）。结论患者术前给予米索前列醇1片舌下含化,2 h后阴道后穹窿塞1片米索前列醇,然后再给患者安定10 mg静脉推注。30 min后,用阿托品0.5 mg＋2%利多卡因10 ml对患者宫颈进行四点封闭,手术时子宫颈软化及松弛程度较对照组明显提高、子宫收缩好、阴道出血量减少、人工流产综合征发生率显著下降。

Objective Observation of misoprostol and lidocaine,atropine,stable in the artificial abortion preoperative and intraoperative used to soften the cervix,relieve pain,reduce bleeding of clinical efficacy,and safetyMethods From December 1,2011 to December 1 2012 since the hospital treated 760 cases of women abortion selected 200 cases,the determination of blood or urine HCG positive,B ultrasonic examination to determine for intrauterine pregnancy,were first pregnancy. At 7- 12 weeks and require termination. It were randomly divided into two groups,the observation group and control group. Observation group of patients with preoperative giving misoprostol contains 1 tablet under the tongue,to the patient after 2 h after vaginal vault 1 metre rope,and then to stable patients with 10 mg intravenous injection,after 30 minutes,0. 5 mg ＋ 2% lidocaine with atropine 10 ml of patients with cervical closed and give massage at 4 o ＇clock,and then for artificial abortion. Results Control group preoperative don＇t do any processing,according to the conventional methods do induced abortion operation. Conclusion Patients with preoperative give misoprostol contains 1 tablet under the tongue,2 h after vaginal fornix after 1 metre rope,and then to settle 10 mg patients with intravenous injection. After 30 minutes,0. 5 mg ＋ 2% lidocaine with atropine 10 ml of patients with cervical closed at 4 o ＇clock,cervix softening and relaxation degree when the operation was obviously improved,good uterine contractions and vaginal haemorrhage amount less,a significant reduction in the incidence of induced abortion syndrome.