山西某医院葡萄球菌属的分布及药物敏感性分析

Distribution and Drug Susceptibility of Staphylococcus in a Hospital from Shanxi Province

目的：了解长治医学院附属和平医院临床分离标本中葡萄球菌属的分布及药物敏感性状况。方法：收集长治医学院附属和平医院检验科2010年1-12月临床就诊部分患者的呼吸道、泌尿道及皮肤软组织等分泌液，采用血琼脂平板培养分离得到各种类型的葡萄球菌的病原学进行回顾性分析。结果：共从临床分离所得葡萄球菌属15种187株，以金黄色葡萄球菌为最多，其次是溶血葡萄球菌、表皮葡萄球菌、人葡萄球菌和缓慢葡萄球菌等。经药物敏感性试验发现，葡萄球菌属细菌对喹努普汀/达福普汀和利奈唑胺有100%的敏感性；对万古霉素、替考拉宁和氟喹诺酮类药物有较高敏感性；对青霉素类抗生素的敏感性相对较低。结论：检测葡萄球菌属对于指导临床上合理用药、防止葡萄球菌属的感染有重要意义。

Objective：To know the distribution and drug susceptibility of the Staphylococcus isolated from clinical specimens for Heping Hospital affiliated to Changzhi Medical College.Methods：The Specimens were collected from clinical laboratory 2010.The blood agar plates were used to culture the strains.And the staphylococcus etiology were analyzed retro-spectively.Results：The Staphylococcus have 187 strains（15 species）.The staphylococcus aureus was the most,followed by Staphylococcus haemolyticus,Staphylococcus epidermidis,Staphylococcus hominis and Staphylococcus lentus,etc.With the drug sensitive test,we found that the Staphylococcus was 100% susceptibility to of Nuputing and Dalfopristin and Linezolid, and was higher susceptibility to Vancomycin,Teicoplanin and Fluoroquinolones and so on.Conclusion：The Staphylococcus were detected in order to guide clinical rational drug using and suppress the infection and outbreak of Staphylococcus.