武汉市东西湖区与羊密切接触人群戊型肝炎病毒感染状况

Investigation on sero-prevalence of Hepatitis E Virus infection among the population contacted closely with sheep in Dongxihu district,Wuhan

目的调查武汉市东西湖区与羊密切接触人群戊型肝炎病毒(HEV)感染状况并分析可能的危险因素,为戊型肝炎(HE)的预防控制提供依据。方法采集与羊密切接触人群和普通人群的血液样本,用酶联免疫吸附试验检测血清HEV-IgG;调查分析两组人群的基本情况和与羊密切接触人群感染HEV的危险因素。结果与羊密切接触人群血液样本145份、HEV-IgG阳性率53.79%,普通人群血液样本158份、HEV-IgG阳性率38.61%,两者差异具有统计学意义。结论武汉市东西湖区与羊密切接触人群HEV既往感染率明显高于普通人群,两者差异具有统计学意义,专职从事畜牧养殖和年龄较大是可能的危险因素。

Objective To Investigate the sero-prevalence of Hepatitis E Virus infection among the population contacted closely with sheep in Dongxihu district, Wuhan, and analyze the possible risk factors to provide the basis for prevention and control of HE. Methods Blood samples, collected from the population contacted closely with sheep, and the general population as control,were tested for anti-HEV IgG by ELISA; basic information of the above two groups, and the risk factors being infected with HEV when closely contacted with sheep were investigated. Results The positive ratio of anti- HEV IgG was 53. 79% ,from 145 blood samples of the population contacted closely with sheep. It was 38. 61% ,from 158 samples of the general population,the difference was significant. Conclusions The HEV infection rate of the population contacted closely with sheep was obviously higher than that of the general population in Dongxihu district, Wuhan, the difference was significant. Those of full-time engaged in animal husbandry and older age might be the risk factors.