2004-2012年南充市梅毒流行特征分析

Epidemiological Characteristics of Syphilis in Nanchong City,2004-2012

目的了解南充市梅毒发病水平和流行特征，为制定梅毒防制策略提供科学依据。方法收集2004—2012年南充市传染病网络直报系统报告梅毒病例，结合辖区某三甲医院就诊一般患者梅毒抗体筛查资料，进行描述流行病学分析。结果2004—2012年南充市累计报告梅毒7396例，死亡1人，年均报告发病率为12．43／10万，年平均增长速度1261．60％，各年度发病率差异有统计学意义（P〈0．01）。报告梅毒病例分期以隐形梅毒最高为2456例（46．71％）。每月均有病例报告，季节性高峰不明显。男女性别比为0．93：1；发病年龄以20—49岁年龄组为主，职业分布以农民为主。年均报告发病率居前3位的县（区）是顺庆区、高坪区和蓬安县。临床就诊一般患者的梅毒抗体筛查阳性率为7．86％。结论南充市2004—2012年梅毒发病率呈逐年上升趋势，应开展以社区基本公共卫生服务为依托的综合干预措施。

Objective To analyze the morbidity level and epidemiological characteristics of syphilis in Nanchong city during 2004 - 2012, and to provide scientific basis for syphilis prevention and control strategies. Methods Cases of syphilis reported in 2004 -2012 through infectious diseases network were collected and data of syphilis antibody test of general patients in a top three hospital were together analyzed with descriptive statistical method. Results There were 7396 cases accumulatively reported in Nanchong during 2004 -2012, with one person died; the annual incidence rate was 12. 43/10^5, with the average annual growth rate as 1261.60%. Statistical significance were found with different incidence among years （P 〈 0.01 ）. In the reported cases of syphilis, the type with the highest incidence （46.71%） was stealth syphilis with a total of 2456; cases were reported in every month and without obvious seasonal peakthrough the year. The male to female ratio for the incidence was 0. 93 ： 1 ; the main onset age was in the 20 -49 age group and the main occupation distribution were farmers. The three districts/counties with top annual report incidence rate were Shunqing district, Gaoping district and Pengan county. The positive rate of syphilis antibody for general patients was 7.86%. Conclusion The incidence of syphilis in Nanchong during 2004 -2012 presented a overall rising trend. Comprehensive prevention measures should be implemented based on community essential public health services.